Time in Cortical Circuits
نویسندگان
چکیده
منابع مشابه
Time in Cortical Circuits.
UNLABELLED Time is central to cognition. However, the neural basis for time-dependent cognition remains poorly understood. We explore how the temporal features of neural activity in cortical circuits and their capacity for plasticity can contribute to time-dependent cognition over short time scales. This neural activity is linked to cognition that operates in the present or anticipates events o...
متن کاملInhibition in cortical circuits
photobleaching reveal that the half-life of stress-granule-associated RNA-binding proteins is very brief, on the order of seconds to minutes, despite the fact that time-lapse microscopy reveals that individual stress granules persist for hours. This rapid shuttling of protein and RNA within stress granules suggests that their mRNP contents are continually sorted via fleeting associations with t...
متن کاملViewpointWiring Optimization in Cortical Circuits
dritic cable attenuation and axon conduction velocity both depend on the square root of " wire " diameter. We find that if we vary the wire fraction while keeping all but one of these quantities fixed, each quantity reaches an extremum when the wire fraction has a value of 3/5. We also have measured the wire fraction from three mouse cortical regions and find that its actual value is 10010 Nort...
متن کاملWiring Optimization in Cortical Circuits
Wiring a brain presents a formidable problem because neural circuits require an enormous number of fast and durable connections. We propose that evolution was likely to have optimized neural circuits to minimize conduction delays in axons, passive cable attenuation in dendrites, and the length of "wire" used to construct circuits, and to have maximized the density of synapses. Here we ask the q...
متن کاملNicotinic modulation of cortical circuits
The ascending cholinergic neuromodulatory system sends projections throughout cortex and has been shown to play an important role in a number of cognitive functions including arousal, working memory, and attention. However, despite a wealth of behavioral and anatomical data, understanding how cholinergic synapses modulate cortical function has been limited by the inability to selectively activa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2015
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.2654-15.2015